Stemcelldoc's Weblog

November 30, 2013

Another ACL Tear Successfully Treated With Stem Cells

The Centeno-Schultz Clinic has previously reported on the successful treatment of ACL tears with stem cell therapy.

Stem cell treatments are an alternative to traditional knee surgery.

S.D. is 38 y/o world-class extreme skier who sustained a complete tear of his ACL and declined surgery.  He underwent 5 prolotherapies in Mexico with minor improvement.

drake stephan

On 7.31.2013 S.D. underwent the Regenexx SD procedure where bone marrow derived cells were injected into the torn ACL.  Due to abnormal neurologic examination and history of intermittent lower back pain also underwent Regenexx PL-Disc where concentrated platelet growth factors were injected around the exiting spinal nerve roots and lumbar discs.

On 9.13.2013 S.D. underwent a booster injection with Regenexx cSCP  injected into the ACL under direct x-ray guidance.

A new MRI was recently performed approximately 4 months post stem cell therapy.

The pre and post treatment images are posted below.  The ACL is outlined in yellow.  Note that the ACL fibers are disorganized and loose in the pre treatment images whereas post treatment the ACL fibers are uniform and tightly organized.  This is consistent with his clinical progress as he reports a reduction in pain and increase in stability.  Muscle weakness remains an issue but is improving with MAT techniques.

Drake. ACL pre and post 2013.sagittal

Drake. ACL pre and post 2013.Coronal

Congratulations to SD who declined surgical repair and opted to utilize his own bone marrow stem cells to repair his torn ACL.  Updates to follow as snow continues to fall and the depth of the powder increases.

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October 2, 2013

Continued Success with ACL Tear Treated with Stem Cells

MM is a 16 y/o athlete who torn her ACL and declined surgical repair.  She opted for Regenexx SD where bone marrow derived stem cells along with platelets are utilized to repair injured tissue.

Regenexx SD has been used successfully in the treatment of ACL tears in other patients.

MM tore her ACL in 2.2013 while playing soccer and underwent stem cell treatment in march 2013.

MRI 3 months post Regenexx SD demonstrated improvement which corresponded with her signficant clinical improvement.

Patient underwent x-ray guided injection of cSCP as a booster in July 2013.

I recently reviewed new knee MRI which is 6 months post stem cell treatment.   It demonstrates continued improvement and healing.  Most importatly there is no ACL tear.  MM is now active and without pain or instability.

Below are the pre, 3 month and 6 month post Regenexx MRI’s.  Note the serial improvement in the ACL fibers which are outlined in yellow.

Slide1

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Most recent MRI report demonstrates no ACL tear.

MM MRI report 2.

Congratulations to MM and her family who embraced stem cell therapy and avoided surgery.

September 6, 2013

Successful Stem Cell Treatment for ACL Tear

At the Centeno-Schultz Clinic we acknowledge that injury to Anterior Cruciate Ligament (ACL) can lead to knee instability, pain, meniscal injury, cartilage damage and restriction in range of motion. Surgical repair is often recommended.

Surgery is not the only option and the problems associated with ACL grafts have been previously discussed.

JP is an active physician who injured his ACL while skiing. MRI of knee was signficant for mid substance disruption of the ACL with signficant swelling and irregularity of the ACL fibers. He had signficant knee pain with restriction in range of motion and used crutches in clinic intermittently.

JP rejected the recommended ACL surgery and opted for stem cell therapy in June 2013. Three months post Regenexx therapy he reports 90% improvement with no restriction in range in motion. MRI post stem cell injection is significant for intact fibers in both the originating and inserting margins with marked improvement in mid substance swelling.

Below are the pre and post MRI’s. The images were taken at the same imaging center. The images on the left are frontal whereas on the right are from the side. The dashed yellow lines outline the ACL. Pre-stem cell injection the ACL fibers are irregular and poorly defined whereas post stem cell injection the ACL fibers are well-organized, tight and well-defined.

ACL Anatomy

Peragine pre and post ACL 1

Peragine pre and post ACL 2

Through stem cell therapy JP is was able to avoid surgery and the lengthy rehabilitation. Yesterday he purchased his season ski pass.
Congratulations!!

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