Stemcelldoc's Weblog

November 27, 2011

Intracranial Hypotension: Treatment with Stem Cells

 Intracranial hypotension is caused by spinal cerebrospinalfluid (CSF) leaks and is known for causing orthostatic headaches. It is most commonly seen in patients who have undergone lumbar punctures (LP’s) or inadverent dural puncture during epidural placment.

Spontaneous spinal cerebrospinal fluid leaks is also an important cause of new headaches in young and middle-aged individuals. The incidence has been estimated at 5 per 100 000 per year,with a peak around age 40 years. Women are affected more commonly than men.

Stem cell therapy in the form of Regenexx SCP  has been utilized in a patient with chronic dural leak.

Clincial improvement to date has been encouraging with an increase in function and decrease in symptoms.

Typical magnetic resonance imaging findings include:

  • subdural fluid collections
  • enhancement of the pachymeninges
  • pituitary hyperemia
  •  sagging of the brain
  • engorgement of venous structures

Myelography is the study of choice to identify the spinal CSF leak.

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