Stemcelldoc's Weblog

April 5, 2009

Adult Stems Cells Improve Heart Function

Two items had major headlines this week:  adult stem cell therapy for cardiac patients and the snow in Vail.  Two recent storms have brought record amounts of snow to Vail.  Words alone can not accurately describe the back bowls!

Back Bowls in Vail

Back Bowls in Vail

Physicians at  Emory University  have demonstrated that infusing bone-marrow-derived, autolgous stem cells in patients who have sustained a heart attack and underwent angioplasty, had an increase in blood flow to the heart.  The study examined the significance of injecting three different amounts of stem cells:  5, 10 and 15 million cells.  At three months, the patients who received higher doses of stem cells showed the greatest improvement in blood flow to the heart.  This is very promising technology and has the potential of re-defining the management of patients with heart disease.

March 31, 2009

Minimal Culture Expansion: A Historial Perspective

The evolution of In-Vitro Fertilization (IVF) illustrates the development of a minimal culture expansion process.  In the late 1970’s, the first IVF was performed.  In the 1990’s, in an effort to improve conception outcomes, fertility specialists elected to extend the cell culture time.  Specifically they extended cell culture to the blastocyst stage which is a more mature developmental phase. In doing so, the fertility specialists transitioned In-Vitro Feritlization from a simple tissue transplant to a cell culture technique.  These specialist maintain that their cell culture techniques are the practice of medicine and not the production of biologic drugs.  No parents who have undergone IVF,  think of their daughters or sons as biologic drugs, do they?

Adult, autologous stem cell therapy was found itself on a similar path.  In an effort to optimize clinical outcomes, some practices expand a patients’ own stem cells thereby increasing the total number of cells available.  Expansion takes 12-14 days and is conducted in a state of the art cell culture lab.  No growth hormone or exogenous products are used to increase the cell count.    If you are a patient who is concerned that this therapy may no longer be available please visit:

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