Stemcelldoc's Weblog

June 15, 2013

Successful Treatment of Knee Osteoarthritis with Prolotherapy

The Centeno-Schultz Clinic offers a variety of non surgical regenerative therapies to treat spine, knee, hip and ankle pain.  The therapies include prolotherapy,  platelet rich plasma and  bone marrow derived stem cells. (Regenexx SD and Regenexx C).

needle injection

Prolotherapy is the injection of a hypertonic solution into a joint, tendon or ligament with the purpose of creating chemical micro-injury.  The micro-injury leads to inflammation and subsequent healing.    At the Centeno-Schultz Clinic prolotherapy is performed under the use of x-ray or MSK ultrasound guidance.

Does prolotherapy work?

Traditional medicine has been skeptical due to lack of good quality studies.

Rabago et al recently published the results of a randomized control study comparing saline injections and exercise to prolotherapy for knee osteoarthritis.’

Ninety patients with known knee osteoarthritis  were randomized to undergo injection therapy of either prolotherapy or saline or in -home exercise.  No baseline differences existed between groups.  At 52 weeks there were statistically differences in the pain scores.  Patients receiving  prolotherapy  improved more (P <.05) at 52 weeks than did  scores for patients receiving saline and exercise .  Patient satisfaction was also high with prolotherapy.

CONCLUSIONS Prolotherapy resulted in clinically meaningful sustained improvement of pain, function, and stiffness scores for knee osteoarthritis compared with blinded saline injections and at-home exercises.

Prolotherapy is an effective alternative to common steroid injections in the treatment of knee osteoarthritis.


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