Stemcelldoc's Weblog

November 16, 2011

Knee Osteoarthritis Grading: Limitations of X-rays

X-rays are able to directly visualize osseous features of osteoarthritis, including osteophytes (bone spurs), sclerosis, and subchondral cysts. They are used in clinical practice to confirm the diagnosis of osteoarthritis.

Osteoarthritis (OA) severity is commonly graded from x-rays using in  the Kellgren and Lawrence scale as previously discussed

MRIs of the knee provide much more detailed information including the quality of cartilage, meniscus integrity, presence or absence of  meniscus tears, fluid collections and integrity of ligaments and tendons.

Do Kallegren-Lawrence scales correlate with findings on MRI?

Yes as evidenced by Agnesi’s article which demonstrated an inverse relationship between KL score and joint space width as measured on MRI.  That is to say that as the osteoarthritis increases as reflected in a higher KL score the more advanced the degeneration in the joint.

Stem cell therapy is an non- surgical alternative for many knee conditionsKnee debridement suregery has been shown to be be no better than a placebo surgery. The larger the portion of the mensicus that is removed the greater the stress that is placed on the joint.  The clinical success of patients who have undergone Regenexx-C, -AD and Regenexx SCP have been previously described.  The use of expanded stem cells, Regenexx-C, has been demonstrated to be safe and not associated with the development of tumors.  The Centeno-Schultz Clinic just published another study which tracked 339 patients for up to 4 years and involved 200 research MRI’s on 50 patients.

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