Stemcelldoc's Weblog

March 25, 2009

Ultrasound And Stem Cell Differentiation

Mesenchymal stem cells have the potential to change into bone, cartilage, ligament or fat.  In a previous blog, I discussed the importance of exercise in providing clues to the mesenchymal stem cells to change into cartilage.

Are there other factors which provide clues to mesenchymal stem cells?

Schumann et. al., demonstrated that low intensity pulsed ultrasound (LIPUS)  made a significant difference in prompting mesenchymal stem cells to morph into cartilage.  At Regenexx, where patients are afforded the opportunity to utilize their own mesenchymal stem cells,  now utilizes LIPUS   in all patients with cartilage damage.  It is critical that the correct stem cells are placed in the correct location and provided every opportunity to prosper as well as to change into the desired tissue.  That is our commitment at Regenexx.


  1. Is LIPUS the same, or at least similar, to using the Thermotex unit? Thanks as always..

    Comment by Mike Nelli — March 25, 2009 @ 6:48 pm

    • The Thermotx is a infra-red device designed to promote an increase in blood flow. It is a different modality and has no ultrasound capability.

      Comment by stemcelldoc — March 26, 2009 @ 7:39 am

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