Stemcelldoc's Weblog

August 24, 2008

Autologous Mesenchymal Stem Cells and Knee Surgery

Filed under: Uncategorized — stemcelldoc @ 6:15 am

Countless numbers of people suffer from knee pain on a daily basis.  When this pain is due to cartilage loss causing bone to rub against bone, the condition is called osteoarthritis.  Until recently, treatments for knee pain secondary to osteoarthritis has been limited. 

Medications alone, such as NSAIDS and narcotics provide temporary, often incomplete relief and can have unwanted side effects such as oversedation and stomach ulcers. 

Injections of steroid and artificial joint fluid, such as Synvisc and Hyalgan, may prove beneficial, but relief is usually temporary.

Prolotherapy, or injection of a dextrose based irritant solution, induces the body’s own healing process, and can offer longer term sympotom relief.

There are several surgical options ranging from microfracture to total knee replacement are intended to offer more definitive, longer term relief from artiritic knee pain.  Thse procedures, however often fall short of their promised pain relief.  Pain after knee surgery can be significant and result in a prolonged recovery period.  While microfracture’s recovery is less than that of knee surgery pain, it’s cartilage growth is often minimal and short lived.

Autologous mesenchymal stem cell therapy is an exciting alternative to knee replacement surgery.  Unlike any of the procedures mentioned above, this procedure actually regrows cartilage and results in reduced knee pain.  There are several successful case studies in the literature which attest to this.

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